The clinical and cost-effectiveness of anakinra for the treatment of rheumatoid arthritis in adults: a systematic review and economic analysis.

@article{Clark2004TheCA,
  title={The clinical and cost-effectiveness of anakinra for the treatment of rheumatoid arthritis in adults: a systematic review and economic analysis.},
  author={W. O. Clark and Paresh Jobanputra and P Barton and Amanda Burls},
  journal={Health technology assessment},
  year={2004},
  volume={8 18},
  pages={iii-iv, ix-x, 1-105}
}
OBJECTIVES To review the evidence of the clinical and cost-effectiveness of anakinra, an interleukin-1 receptor antagonist (IL-1Ra), for the treatment of rheumatoid arthritis (RA) in adults. DATA SOURCES Electronic bibliographic databases. Scrip, Food and Drug Administration (FDA) submissions for new drug applications, European Agency for the Evaluation of Medicinal Products (EMEA) reports and the pharmaceutical company submission to the National Institute for Clinical Excellence. REVIEW… CONTINUE READING
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