The claustrum coordinates cortical slow-wave activity

@article{Narikiyo2020TheCC,
  title={The claustrum coordinates cortical slow-wave activity},
  author={Kimiya Narikiyo and Rumiko Mizuguchi and Ayako Ajima and Momoko Shiozaki and Hiroki Hamanaka and Joshua P. Johansen and Kensaku Mori and Yoshihiro Yoshihara},
  journal={Nature Neuroscience},
  year={2020},
  volume={23},
  pages={741-753}
}
During sleep and awake rest, the neocortex generates large-scale slow-wave (SW) activity. Here, we report that the claustrum coordinates neocortical SW generation. We established a transgenic mouse line that enabled the genetic interrogation of a subpopulation of claustral glutamatergic neurons. These neurons received inputs from and sent outputs to widespread neocortical areas. The claustral neuronal firings mostly correlated with cortical SW activity. In vitro optogenetic stimulation of the… 
Sleep slow oscillation and inhibition
  • I. Timofeev
  • Chemistry, Medicine
    The Journal of physiology
  • 2020
TLDR
Evidence is provided for a strong involvement of GABAB inhibition in control of the cortical slow oscillation and a recent study demonstrated that claustrum neurons provide a very efficient global control of cortical slow wave activity.
Topographic gradients define the projection patterns of the claustrum core and shell in mice
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Topographic gradients define the projection patterns of the claustrum core and shell in mice
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