The circulating non-coding RNA landscape for biomarker research: lessons and prospects from cardiovascular diseases

@article{Stpie2018TheCN,
  title={The circulating non-coding RNA landscape for biomarker research: lessons and prospects from cardiovascular diseases},
  author={E Stępień and M C Costa and Szczepan Kurc and Anna Dr{\'o}żdż and Nuno Cortez-Dias and Francisco Javier Enguita},
  journal={Acta Pharmacologica Sinica},
  year={2018},
  volume={39},
  pages={1085-1099}
}
Pervasive transcription of the human genome is responsible for the production of a myriad of non-coding RNA molecules (ncRNAs) some of them with regulatory functions. The pivotal role of ncRNAs in cardiovascular biology has been unveiled in the last decade, starting from the characterization of the involvement of micro-RNAs in cardiovascular development and function, and followed by the use of circulating ncRNAs as biomarkers of cardiovascular diseases. The human non-coding secretome is… CONTINUE READING
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