• DOI:10.1146/annurev.genom.7.080505.115610
Corpus ID: 40223129

The ciliopathies: an emerging class of human genetic disorders.

@article{Badano2006TheCA,
  title={The ciliopathies: an emerging class of human genetic disorders.},
  author={Jose L. Badano and Norimasa Mitsuma and Phil L Beales and Nicholas Katsanis},
  journal={Annual review of genomics and human genetics},
  year={2006},
  volume={7},
  pages={
          125-48
        }
}

Jose L. Badano, Norimasa Mitsuma, +1 author Nicholas Katsanis

Published in

Annual review of genomics and…

2006

Medicine, Biology

Cilia and flagella are ancient, evolutionarily conserved organelles that project from cell surfaces to perform diverse biological roles, including whole-cell locomotion; movement of fluid; chemo-, mechano-, and photosensation; and sexual reproduction. Consistent with their stringent evolutionary conservation, defects in cilia are associated with a range of human diseases, such as primary ciliary dyskinesia, hydrocephalus, polycystic liver and kidney disease, and some forms of retinal… CONTINUE READING

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