The chronic debate over Lyme disease

  title={The chronic debate over Lyme disease},
  author={Coco Ballantyne},
  journal={Nature Medicine},
nature medicine volume 14 | number 11 | november 2008 1135 It was 1994 and life could not have been better for Alita Lyons, an aspiring biochemist from Manhattan. As a child, Lyons had dreamed of working in science, and now, at age 27, she had landed her dream job: studying hepatitis C in a laboratory at the Weill Medical College of Cornell University in New York. All day and sometimes late into the night, Lyons sat at the lab bench pipetting chemicals into test tubes and running carefully… 

Post-treatment Lyme Disease as a Model for Persistent Symptoms in Lyme Disease

Post-treatment Lyme disease represents a narrow, defined, mechanistically-neutral subset of this larger, more heterogeneous group of patients, and is a useful definition in research settings as an initial subgroup of study.

Scientific evidence and best patient care practices should guide the ethics of Lyme disease activism

Allegations of conflict of interest against the IDSA resemble those made against the National Institutes of Health, the Food and Drug Administration and the Centers for Disease Control and Prevention in 2000, which were found to be baseless.

Treatment of Lyme borreliosis

If the infection is manifest, then treatment strategies should target not only the pathogen by using antibiotics but also the chronic inflammation by using anti-inflammatory drugs.

Lyme Borreliosis in Canada: Biological Diversity and Diagnostic Complexity from an Entomological Perspective

Opportunities abound for entomologists to contribute to documenting the diversity of the players and their interactions in this devilishly complex disease.

Bicarbonate therapy for infants.

  • D. Bourchier
  • Medicine, Psychology
    The Journal of pediatrics
  • 2011

Experiences of patients identifying with chronic Lyme disease in the healthcare system: a qualitative study

Four major themes emerged from participants’ descriptions of their experiences and perceptions: changes in health status and the social impact of chronic Lyme disease, doubts about recovery and the future, contrasting doctor-patient relationships, and the use of unconventional therapies to treat Chronic Lyme disease.

Lyme borreliosis ( LB ) is a potentially debilitating illness that is typically vectored by ixodid ticks ( Acari : Ixodida : Ixodidae ) and caused by infection by the spirochete Borrelia burgdorferi

Opportunities abound for entomologists to contribute to documenting the diversity of the players and their interactions in this devilishly complex disease.

5-Lipoxygenase–Deficient Mice Infected with Borrelia burgdorferi Develop Persistent Arthritis

It is demonstrated that products of the 5- LO metabolic pathway are not required for the development of disease in all models of arthritis and that caution should be used when targeting 5-LO as therapy for inflammatory diseases.

An estimate of Lyme borreliosis incidence in Western Europe†

LB is a continually emerging disease and the most common zoonotic infection in Western Europe approaching endemic proportions in many European countries and Concordant and well-conducted surveillance and disease awareness should continue to be encouraged to monitor LB, as tick numbers and activity are increasing, leading to greater risks of infection.

Australian penguin ticks screened for novel Borrelia species.