The chromosomal localization of human β-galactosidase revisited: a locus for β-galactosidase on human chromosome 3 and for its protective protein on human chromosome 22

@article{Sips1985TheCL,
  title={The chromosomal localization of human β-galactosidase revisited: a locus for β-galactosidase on human chromosome 3 and for its protective protein on human chromosome 22},
  author={Herman J. Sips and H. A. de Wit-Verbeek and Joyce C. de Wit and Andries Westerveld and Hans Galjaard},
  journal={Human Genetics},
  year={1985},
  volume={69},
  pages={340-344}
}
A series of man-Chinese hamster and man-mouse somatic cell hybrids was investigated to study the localization of the genes coding for the human lysosomal enzyme β-galactosidase (EC 3.2.1.23) and for its protective protein. Using a monoclonal antibody, raised against human placental β-galactosidase, it was observed that the structural locus for the β-galactosidase polypeptide is located on chromosome 3. The nature of the involvement of chromosome 22 in the expression of human β-galactosidase was… CONTINUE READING
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