The chromatin remodelling complex FACT associates with actively transcribed regions of the Arabidopsis genome.

@article{Duroux2004TheCR,
  title={The chromatin remodelling complex FACT associates with actively transcribed regions of the Arabidopsis genome.},
  author={Meg Duroux and Andreas Houben and Kamil Růzicka and Jiř{\'i} Friml and Klaus D Grasser},
  journal={The Plant journal : for cell and molecular biology},
  year={2004},
  volume={40 5},
  pages={660-71}
}
The packaging of the genomic DNA into chromatin in the cell nucleus requires machineries that facilitate DNA-dependent processes such as transcription in the presence of repressive chromatin structures. Using co-immunoprecipitation we have identified in Arabidopsis thaliana cells the FAcilitates Chromatin Transcription (FACT) complex, consisting of the 120-kDa Spt16 and the 71-kDa SSRP1 proteins. Indirect immunofluorescence analyses revealed that both FACT subunits co-localize to nuclei of the… CONTINUE READING
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