The cholinergic inhibition of afterhyperpolarization in rat hippocampus is independent of cAMP-dependent protein kinase.

Abstract

The possible involvement of protein kinase A (PKA) in the muscarinic inhibition of the slow afterhyperpolarizing current (IAHP) was investigated in rat hippocampal pyramidal cells. IAHP was recorded using the whole cell method in hippocampal slices, and Rp-cAMPS, a PKA antagonist, was applied intracellularly. The inhibition of IAHP by carbachol was not… (More)

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@article{Blitzer1994TheCI, title={The cholinergic inhibition of afterhyperpolarization in rat hippocampus is independent of cAMP-dependent protein kinase.}, author={Rachel Blitzer and T. Wong and Rabin Katan Nouranifar and Ehud M. Landau}, journal={Brain research}, year={1994}, volume={646 2}, pages={312-4} }