The cholinergic gene locus.

  title={The cholinergic gene locus.},
  author={Lee E. Eiden},
  journal={Journal of neurochemistry},
  volume={70 6},
Messenger RNAs and the cognate gene(s) encoding choline acetyltransferase (ChAT) and the vesicular acetylcholine transporter (VAChT) have been cloned from mammals and several other animal classes in the last decade. These have provided molecular tools for investigating acetylcholine synthesis and packaging into synaptic vesicles, the genesis of cholinergic vesicles, and the development and senescence of the cholinergic nervous system. VAChT and ChAT have been found to share a common gene locus… CONTINUE READING
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