The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery.

@article{Davis2008TheCO,
  title={The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery.},
  author={Nicole M. Davis and Natasza A Kurpios and Xiaoxia Sun and Jerome Gros and James F. Martin and Clifford J Tabin},
  journal={Developmental cell},
  year={2008},
  volume={15 1},
  pages={134-45}
}
We have investigated the structural basis by which the counterclockwise direction of the amniote gut is established. The chirality of midgut looping is determined by left-right asymmetries in the cellular architecture of the dorsal mesentery, the structure that connects the primitive gut tube to the body wall. The mesenchymal cells of the dorsal mesentery are more condensed on the left side than on the right and, additionally, the overlying epithelium on the left side exhibits a columnar… CONTINUE READING

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