• DOI:10.1016/j.mcn.2013.04.009
Corpus ID: 21526309

The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain

@article{Vo2013TheCA,
  title={The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain},
  author={T. Vo and D. Carulli and E. Ehlert and Jessica C F Kwok and J. Verhaagen},
  journal={Molecular and Cellular Neuroscience},
  year={2013},
  volume={56},
  pages={186-200}
}

T. Vo, D. Carulli, +2 authors J. Verhaagen

Published 2013

Biology, Medicine

Molecular and Cellular Neuroscience

In the adult rodent brain, subsets of neurons are surrounded by densely organised extracellular matrix called perineuronal nets (PNNs). PNNs consist of hyaluronan, tenascin-R, chondroitin sulphate proteoglycans (CSPGs), and the link proteins Crtl1 and Bral2. PNNs restrict plasticity at the end of critical periods and can be visualised with Wisteria floribunda agglutinin (WFA). Using a number of antibodies raised against the different regions of semaphorin3A (Sema3A) we demonstrate that this… CONTINUE READING

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