The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

@article{Tachibana1998TheCR,
  title={The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract},
  author={Kazunobu Tachibana and Seiichi Hirota and Hisashi Iizasa and Hisahiro Yoshida and Kenji Kawabata and Yuki Kataoka and Yukihiko Kitamura and Kouji Matsushima and Nobuaki Yoshida and Shin-ichi Nishikawa and Tadamitsu Kishimoto and Takashi Nagasawa},
  journal={Nature},
  year={1998},
  volume={393},
  pages={591-594}
}
Vascularization of organs generally occurs by remodelling of the preexisting vascular system during their differentiation and growth to enable them to perform their specific functions during development. The molecules required by early vascular systems, many of which are receptor tyrosine kinases and their ligands, have been defined by analysis of mutant mice1,2,3. As most of these mice die during early gestation before many of their organs have developed, the molecules responsible for… CONTINUE READING
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