The chemokine receptor CCR4 is expressed and associated with a poor prognosis in patients with gastric cancer.

@article{Lee2009TheCR,
  title={The chemokine receptor CCR4 is expressed and associated with a poor prognosis in patients with gastric cancer.},
  author={Jun Ho Lee and Young-Suk Cho and Ji Young Lee and Myoung Cheorl Kook and Jong-Whan Park and Byung-ho Nam and Jae-Moon Bae},
  journal={Annals of surgery},
  year={2009},
  volume={249 6},
  pages={933-41}
}
OBJECTIVES There is increasing evidence that chemokines and chemokine receptors are causally involved in the metastasis of cancer. Little is known about the possible role of chemokine receptors in the metastasis of gastric cancer. The aim of this study was to investigate the expression of chemokine receptors and their prognostic role in patients with gastric cancer. METHODS We screened the expression of CCR and CXCR chemokine receptors in 12 gastric cancer cell lines using the semi… CONTINUE READING