The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases.

@article{Wells1997TheCI,
  title={The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases.},
  author={Timothy N. C. Wells and Manuel C. Peitsch},
  journal={Journal of leukocyte biology},
  year={1997},
  volume={61 5},
  pages={
          545-50
        }
}
The chemokine superfamily is a large group of more than 30 small proteins. Many of these were originally identified because of their role in the selective recruitment and activation of leukocytes during inflammation. More recently, some of the chemokine receptors and ligands have been implicated in the mechanism of viral infection for primate lentiviruses such as HIV-1. From the original identification of interleukin-8 (IL-8; the most studied member of the superfamily), the number of new family… CONTINUE READING

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