The chemokine growth-regulated oncogene-alpha promotes spinal cord oligodendrocyte precursor proliferation.

@article{Robinson1998TheCG,
  title={The chemokine growth-regulated oncogene-alpha promotes spinal cord oligodendrocyte precursor proliferation.},
  author={Shenandoah Robinson and Marie Tani and Robert M. Strieter and Richard M Ransohoff and Robert H. Miller},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 24},
  pages={10457-63}
}
Chemokines, (chemotactic cytokines) are a family of regulatory molecules involved in modulating inflammatory responses. Here we demonstrate that the chemokine growth-regulated oncogene-alpha (GRO-alpha) is a potent promoter of oligodendrocyte precursor proliferation. The proliferative response of immature spinal cord oligodendrocyte precursors to their major mitogen, platelet derived growth factor (PDGF), is dramatically enhanced by GRO-alpha present in spinal cord conditioned medium. One… CONTINUE READING

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Chemokines. Blood 90:909–928

  • B Rollins
  • 1997
Highly Influential
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