The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.

@article{Bonacchi2003TheCC,
  title={The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.},
  author={Andrea Bonacchi and Ilaria Petrai and Raffaella M S Defranco and Elena Lazzeri and Francesco Annunziato and Eva Efsen and Lorenzo Cosmi and Paola Romagnani and Stefano Milani and Paola Failli and Giacomo Batignani and F Leonarda Liotta and Giacomo Laffi and Massimo Pinzani and Paolo Gentilini and Fabio Marra},
  journal={Gastroenterology},
  year={2003},
  volume={125 4},
  pages={1060-76}
}
BACKGROUND AND AIMS The chemokines CCL19 and CCL21 bind CCR7, which is involved in the organization of secondary lymphoid tissue and is expressed during chronic tissue inflammation. We investigated the expression of CCL21 and CCR7 in chronic hepatitis C. The effects of CCL21 on hepatic stellate cells (HSCs) were also studied. METHODS Expression of CCL21… CONTINUE READING