The chemically inducible plant cytochrome P450 CYP76B1 actively metabolizes phenylureas and other xenobiotics

@article{Robineau1998TheCI,
  title={The chemically inducible plant cytochrome P450 CYP76B1 actively metabolizes phenylureas and other xenobiotics},
  author={Robineau and Batard and Nedelkina and Cabello-Hurtado and LeRet and Sorokine and Didierjean and Werck-Reichhart},
  journal={Plant physiology},
  year={1998},
  volume={118 3},
  pages={
          1049-56
        }
}
  • Robineau, Batard, +5 authors Werck-Reichhart
  • Published 1998
  • Biology, Medicine
  • Plant physiology
  • Cytochrome P450s (P450s) constitute one of the major classes of enzymes that are responsible for detoxification of exogenous molecules both in animals and plants. On the basis of its inducibility by exogenous chemicals, we recently isolated a new plant P450, CYP76B1, from Jerusalem artichoke (Helianthus tuberosus) and showed that it was capable of dealkylating a model xenobiotic compound, 7-ethoxycoumarin. In the present paper we show that CYP76B1 is more strongly induced by foreign compounds… CONTINUE READING
    118 Citations
    Plant cytochrome P450-mediated herbicide metabolism
    • 149
    Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenylurea herbicides.
    • 152
    • PDF
    Plant cytochrome P450s: nomenclature and involvement in natural product biosynthesis
    • 24
    • PDF
    Engineering Herbicide Metabolism in Tobacco and Arabidopsis with CYP76B1, a Cytochrome P450 Enzyme from Jerusalem Artichoke1
    • 129
    • Highly Influenced
    • PDF

    References

    SHOWING 1-10 OF 37 REFERENCES
    Metabolism of Herbicides by Cytochrome P450 in Corn
    • M. Barrett
    • Chemistry, Medicine
    • Drug metabolism and drug interactions
    • 1995
    • 56
    Plant Cytochrome P450 Monooxygenases
    • 286