The characteristics of quality of life impairment in adult growth hormone (GH)-deficient survivors of cancer and their response to GH replacement therapy.

@article{Mukherjee2005TheCO,
  title={The characteristics of quality of life impairment in adult growth hormone (GH)-deficient survivors of cancer and their response to GH replacement therapy.},
  author={Annice Mukherjee and S Tolhurst-Cleaver and William J. Ryder and Linda E Smethurst and Stephen M. Shalet},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 3},
  pages={1542-9}
}
We studied 50 (27 women and 23 men) GH-deficient (GHD) cancer survivors and 47 (24 women and 23 men) GHD patients with pituitary pathologies. All GHD patients were considered for GH replacement on the basis of subjectively poor quality of life (QOL). Primary outcome measures were scores of QOL instruments psychological general well-being schedule (PGWB) and assessment of GH deficiency in adults (AGHDA) at baseline and early (6-13 months) and long-term (24-77 months) treatment follow-up. Of… CONTINUE READING

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Reviewing the safety of GH replacement therapy in adults.

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