[The characteristics of iron metabolism under iron-deficiency anemia and chronic disorders anemia].

Abstract

The study investigated the issues of iron metabolism under iron-deficiency anemia and chronic disorders anemia and dependencies of production of IL-1? and sICAM-1 immunoinflammatory markers from degree of severity and duration of anemia. The study data indicates that under iron-deficiency anemia lactoferrin and sICAM-1 are the negative regulators of hemopoiesis. The inhibition of transferrin expression by the proinflammatory cytokines is one of the causes of inefficient hemopoiesis under chronic disorders anemia.

Cite this paper

@article{Smorkalova2011TheCO, title={[The characteristics of iron metabolism under iron-deficiency anemia and chronic disorders anemia].}, author={E V Smorkalova and L F Aznabaeva and V I Nikulicheva and G Sh Safuanova and A N Chepurnaia}, journal={Klinicheskaia laboratornaia diagnostika}, year={2011}, volume={7}, pages={30-2} }