The changing shape of mitochondrial apoptosis.


Mitochondria are key organelles in conversion of energy, regulation of cellular signaling and amplification of programmed cell death. The anatomy of the organelle matches this functional versatility in complexity and is modulated by the concerted action of proteins that impinge on its fusion-fission equilibrium. A growing body of evidence implicates changes… (More)
DOI: 10.1016/j.tem.2009.03.007


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