• DOI:10.1136/jnnp-2016-314495
Corpus ID: 52871105

The changing picture of amyotrophic lateral sclerosis: lessons from European registers

@article{Hardiman2017TheCP,
  title={The changing picture of amyotrophic lateral sclerosis: lessons from European registers},
  author={O. Hardiman and A. Al-Chalabi and C. Brayne and E. Beghi and L. H. van den Berg and A. Chi{\`o} and Sarah Martin and G. Logroscino and J. Rooney},
  journal={Journal of Neurology, Neurosurgery, and Psychiatry},
  year={2017},
  volume={88},
  pages={557 - 563}
}

O. Hardiman, A. Al-Chalabi, +6 authors J. Rooney

Published 2017

Medicine

Journal of Neurology, Neurosurgery, and Psychiatry

Prospective population based-registers of amyotrophic lateral sclerosis (ALS) have operated in Europe for over two decades, and have provided important insights into our understanding of ALS. Here, we review the benefits that population registers have brought to the understanding of the incidence, prevalence, phenotype and genetics of ALS and outline the core operating principles that underlie these registers and facilitate international collaboration. Going forward, we offer lessons learned… CONTINUE READING

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