The changing epidemiology of resistance.

@article{Hawkey2009TheCE,
  title={The changing epidemiology of resistance.},
  author={Peter M.K. Hawkey and Annie M Jones},
  journal={The Journal of antimicrobial chemotherapy},
  year={2009},
  volume={64 Suppl 1},
  pages={i3-10}
}
Antibiotic resistance is now a linked global problem. Dispersion of successful clones of multidrug resistant (MDR) bacteria is common, often via the movement of people. Local evolution of MDR bacteria is also important under the pressure of excessive antibiotic use, with horizontal gene transfer providing the means by which genes such as bla(CTX-M) spread amongst different bacterial species and strains. Beta-lactamase production is a common resistance mechanism in Gram-negative bacteria, and… CONTINUE READING
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