The change of nuclear LC3 distribution in acute myeloid leukemia cells.

@article{Guo2018TheCO,
  title={The change of nuclear LC3 distribution in acute myeloid leukemia cells.},
  author={Wenjian Guo and Jingrui Jin and Jiajia Pan and Rongxing Yao and Xia Ll and Xin Huang and Zhixing Ma and Sujuan Huang and Xiao Yan and Jie Jin and Aishu Dong},
  journal={Experimental cell research},
  year={2018},
  volume={369 1},
  pages={
          69-79
        }
}
Making sure the change of nuclear LC3 distribution in the autophagy of acute myeloid leukemia (AML) cell and finding out the regulation mechanism may lead to a breakthrough for killing AML cells. Western blots were performed to assess the expression of autophagy proteins. Changes in the LC3 distribution were monitored by immunofluorescence assays together with western blots, and the expression levels of Sirt1, DOR, Beclin1, HMGB1, and AMPK mRNA were detected via fluorescent quantitative PCR… CONTINUE READING

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