The challenges of oral drug delivery via nanocarriers

  title={The challenges of oral drug delivery via nanocarriers},
  author={J. Reinholz and K. Landfester and V. Mailaender},
  journal={Drug Delivery},
  pages={1694 - 1705}
  • J. Reinholz, K. Landfester, V. Mailaender
  • Published 2018
  • Chemistry, Medicine
  • Drug Delivery
  • Abstract The oral application of pharmaceuticals is unarguably the most convenient method of application. Especially for protein- or peptide-based drugs, however, the effectiveness is significantly reduced due to enzymatic digestion in the stomach as well as a poor bioavailability in the small intestine. For these difficult formulations, the encapsulation into nanocarriers would protect the sensitive drug and thus could considerably improve the efficiency of oral drug delivery. In the last… CONTINUE READING
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