The challenges of containing SARS-CoV-2 via test-trace-and-isolate

@article{Contreras2021TheCO,
  title={The challenges of containing SARS-CoV-2 via test-trace-and-isolate},
  author={Sebasti{\'a}n Contreras and Jonas Dehning and Matthias Loidolt and Johannes Zierenberg and F. Paul Spitzner and Jorge-Humberto Urrea-Quintero and Sebastian B. Mohr and Michael Wilczek and Michael Wibral and Viola Priesemann},
  journal={Nature Communications},
  year={2021},
  volume={12}
}
Without a cure, vaccine, or proven long-term immunity against SARS-CoV-2, test-trace-and-isolate (TTI) strategies present a promising tool to contain its spread. For any TTI strategy, however, mitigation is challenged by pre- and asymptomatic transmission, TTI-avoiders, and undetected spreaders, which strongly contribute to ”hidden" infection chains. Here, we study a semi-analytical model and identify two tipping points between controlled and uncontrolled spread: (1) the behavior-driven… Expand

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