The challenge of recalcitrant acute otitis media: pathogens, resistance, and treatment strategy.


Recalcitrant acute otitis media (AOM), including 2 well-defined and sometimes related entities (persistent AOM and recurrent AOM), is a common pediatric problem. Episodes of AOM in children with either persistent or recurrent AOM were shown to be associated with recovery of middle ear fluid bacterial pathogens (particularly Streptococcus pneumoniae) with… (More)


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