Molecular aspects of milk allergens and their role in clinical events
- Chemistry, MedicineAnalytical and bioanalytical chemistry
AbstractMilk allergy is the most frequent food allergy in childhood. Even though cases of newly developed milk allergy in adulthood are known, this allergy is less frequent in adults since it is…
Comparative evaluation of allergic sensitization to milk proteins of cow, buffalo and goat
Cow’s Milk Allergens and Technologies to Control Allergenicity
Various approaches have been applied to reduce the allergenicity of cow’s milk proteins, such as heat treatment, glycation, protease hydrolysis and lactobacillus fermentation, but these treatments were able to reduced the allenicity of milk proteins only partly.
Donkey milk production: state of the art
Clinical studies have demonstrated that donkey milk could substitute breast feeding in infants affected by severe Ig-E mediated milk allergies, and in these subjects, donkey milk is not only useful, but also safer than other types of milk.
Bovine Milk Allergens: A Comprehensive Review.
- Medicine, ChemistryComprehensive reviews in food science and food safety
Significant research advances on cow milk allergy are explored, focusing on prevalence, diagnosis, and therapy, as well as the effects of processing, food matrix, and digestibility on milk allergenicity.
Comparison of the Allergenicity and Immunogenicity of Camel and Cow’s Milk—A Study in Brown Norway Rats
- Biology, MedicineNutrients
Camel milk could be a promising alternative to cow’s milk-based hypoallergenic infant formulas due to a low cross-reactivity and similarity in their inherent immunogenicity, sensitising and eliciting capacity.
Comparison of the immunogenicity of yak milk and cow milk
Results indicated that Maiwa yak milk protein may less allergenic than cow milk protein in mice.
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Specificity of the Human IgE Response to the Different Purified Caseins in Allergy to Cow’s Milk Proteins
- Medicine, BiologyInternational Archives of Allergy and Immunology
The results suggest that both distinct and common epitopes may occur on these different caseins and the major site of phosphorylation which is the most conserved domain in three caseins could be involved in the IgE response to casein and in immunocross-reactivity between these proteins.
The balance between caseins and whey proteins in cow's milk determines its allergenicity.
- Medicine, ChemistryJournal of dairy science
The results suggest that the balance between caseins and whey proteins plays an important role in the sensitization capacity ofcow's milk, and its modification might be a way to reduce the allergenicity of cow's milk.
Immunologic and Allergic Properties of Cows' Milk Proteins in Humans.
- Biology, MedicineJournal of food protection
The presence of circulating antibodies to cows' milk proteins of the IgG, IgA and IgM classes is not clinically significant, and such antibodies are found in both normal and allergic individuals.
Allergen‐Specific IgE Antibodies against Antigenic Components in Cow Milk and Milk Substitutes
Crossed radioimmunoelectrophoresis (CRIE) was used to study the presence of scrum IgE against antigenic components of Cow milk in 21 selected milk‐allergic patients, finding that six of the milk substitutes did not differ significantly from cow milk in antibody binding, but the two hydrolysed casein products.
Allergenicity of α‐caseins from cow, sheep, and goat
The milk of goat and sheep harbor an allergic potential and is not suitable for the nutrition of milk‐allergic patients, on the basis of the small differences in their primary structure.
Allergenicity of alpha-caseins from cow, sheep, and goat.
The milk of goat and sheep harbor an allergic potential and is not suitable for the nutrition of milk-allergic patients, and inhibition of the IgE binding to bovine alpha-casein with alpha- Casein from cow, goat, and sheep revealed that the alpha- casein from these species are highly cross-reactive.
Allergenicity of goat's milk in children with cow's milk allergy.
- MedicineThe Journal of allergy and clinical immunology
Identification of casein as the major allergenic and antigenic protein of cow's milk
- Chemistry, MedicineAllergy
The results presented here strongly suggest that casein is the major allergenic component of cow's milk.
Cow's milk allergy: therapeutic options and immunological aspects.
- MedicineEuropean journal of clinical nutrition
The clinical diagnosis of cow's milk allergy is difficult because of the great diversity and varying severity of symptoms and is often based on criteria which is then confirmed by challenge withcow's milk.