The cervical mucus plug: Structured review of the literature

@article{Becher2009TheCM,
  title={The cervical mucus plug: Structured review of the literature},
  author={Naja Becher and Kristina M. Adams Waldorf and Merete Hein and Niels Uldbjerg},
  journal={Acta Obstetricia et Gynecologica Scandinavica},
  year={2009},
  volume={88}
}
The cervical mucus plug is a large, complex structure within the cervical canal that is shed shortly before or during labor. We propose that the cervical mucus plug fulfills critical ‘gate‐keeper’ functions based on its physical and immunologic properties, which help prevent ascending infection and preterm labor. The viscoelastic properties of the cervical mucus plug are determined by mucins (large glycoproteins), which can inhibit viral replication and exclude larger molecules and bacteria by… Expand
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TLDR
The cervical mucus plug is not only a mechanical but also a chemical barrier to infection that ascends from the vagina, which suggests a host defense function, but few relevant data are available. Expand
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TLDR
If the role of the cervical mucus in the capacitation of the spermatozoa and the mechanism of fertilization is established, it might explain some cases of infertility and cervical cancer, and may be useful in the development of alternative forms of contraception. Expand
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TLDR
Cervical mucus glycoproteins may be viewed as a linear array of oligosaccharide-rich 'clusters' alternating with structures reminiscent of a globular protein, which is more sensitive to proteolysis than other mucus gel structures. Expand
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A low-molecular substance with antibacterial activity in the cervical mucus plug may protect the fetus against ascending infections. Expand
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TLDR
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TLDR
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TLDR
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The ultrastructure of the high viscosity phase of human cervical mucus was studied by scanning electronmicroscopy. In the normal woman, sequential mucus samples taken throughout the menstrual cycleExpand
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TLDR
It is fairly well possible that the significant differences in the PGE2 and PGF2 alpha values are causally related to the higher rate of preterm labor in women with the commonplace infection of bacterial vaginosis. Expand
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