The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type.

@article{Silverberg2001TheCF,
  title={The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type.},
  author={Gerald D. Silverberg and Gary Heit and Stephen Huhn and Richard A. Jaffe and Steven D Chang and Helen Bronte-Stewart and Edward B. Rubenstein and Kate Possin and Turandot Saul},
  journal={Neurology},
  year={2001},
  volume={57 10},
  pages={1763-6}
}
OBJECTIVE To evaluate the production rate of CSF in patients with differing disease states. METHODS The authors measured the production rate of CSF in three groups of patients: five patients with PD below age 60 (aged 51 +/- 4 years, mean +/- SD), nine with PD over age 60 (aged 69 +/- 6 years, mean +/- SD), and seven with dementia of the Alzheimer's type (AD) (aged 72 +/- 9 years, mean +/- SD). This method, based on the Masserman technique, employs ventricular rather than a lumbar access to… CONTINUE READING

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