The cerebral and cardiovascular effects of cisatracurium and atracurium in neurosurgical patients.

@article{Schramm1998TheCA,
  title={The cerebral and cardiovascular effects of cisatracurium and atracurium in neurosurgical patients.},
  author={Winfrid Schramm and A Papousek and Andrea Michalek-Sauberer and Thomas Czech and Udo M Illievich},
  journal={Anesthesia and analgesia},
  year={1998},
  volume={86 1},
  pages={123-7}
}
UNLABELLED Drugs for neurosurgical patients should not increase intracranial pressure (ICP) or change cerebral perfusion pressure (CPP) and cerebral blood flow. This double-blind, cross-over study compares the effects of a single (3 x effective dose producing 95% twitch depression) intravenous bolus dose of cisatracurium 0.15 mg/kg with atracurium 0.75 mg/kg on mean red blood cell flow velocity in the middle cerebral artery (CBFV; transcranial Doppler), ICP (intraventricular or intraparenchymal… CONTINUE READING