The cerebellum in Alzheimer's disease.

  title={The cerebellum in Alzheimer's disease.},
  author={Andrew J. Larner},
  journal={Dementia and geriatric cognitive disorders},
  volume={8 4},
The cerebellum is a relatively neglected area of the Alzheimer's disease (AD) brain, probably because it was formerly thought to be spared by the disease. However, a number of pathological changes have now been revealed in the AD cerebellum, principally by immunocytochemical studies, including widespread deposits of diffuse amyloid, ubiquitin-immunoreactive dystrophic neurites, and increased microglia, but tau-immunoreactive neurofibrillary tangles have not been seen. Although the observed… CONTINUE READING


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