The centromeric K-type repeat and the central core are together sufficient to establish a functional Schizosaccharomyces pombe centromere.

@article{Baum1994TheCK,
  title={The centromeric K-type repeat and the central core are together sufficient to establish a functional Schizosaccharomyces pombe centromere.},
  author={Mary Baum and V K Ngan and Louise A Clarke},
  journal={Molecular biology of the cell},
  year={1994},
  volume={5 7},
  pages={747-61}
}
The DNA requirements for centromere function in fission yeast have been investigated using a minichromosome assay system. Critical elements of Schizosaccharomyces pombe centromeric DNA are portions of the centromeric central core and sequences within a 2.1-kilobase segment found on all three chromosomes as part of the K-type (K/K"/dg) centromeric repeat. The S. pombe centromeric central core contains DNA sequences that appear functionally redundant, and the inverted repeat motif that flanks the… CONTINUE READING
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