The centromere specific histone CENP-A is selectively retained in discrete foci in mammalian sperm nuclei

Abstract

The 17 kDa human autoantigen designated CENP-A is a centromere specific histone. We show here that CENP-A is present in tissue of bovine origin, and that it is quantitatively retained in mature spermatozoa. This result is striking, as a prominent feature of spermatogenesis in mammals is the replacement of most somatic and testes specific histones with… (More)
DOI: 10.1007/BF00337600

Topics

4 Figures and Tables