The central role of monocytes in the pathogenesis of sepsis: consequences for immunomonitoring and treatment.

Abstract

Despite important advances in critical care medicine during the last two decades, the mortality rate of sepsis has remained high, probably because the pathogenesis of sepsis is still incompletely understood. Recent studies have shown that sepsis is a bimodal entity. The first phase is characterized by the systemic release of pro-inflammatory cytokines such… (More)

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