The cellular pathway of CD1e in immature and maturing dendritic cells.

@article{Angnieux2005TheCP,
  title={The cellular pathway of CD1e in immature and maturing dendritic cells.},
  author={Catherine Ang{\'e}nieux and Vincent Fraisier and Blandine Ma{\^i}tre and Victor Racine and Nicole N van der Wel and Dominique Fricker and Fabienne Proamer and Martin Sachse and J. -P Cazenave and Peter Edzard Peters and Bruno Goud and Daniel Hanau and Jean-Baptiste Sibarita and Jean Salamero and Henri de la Salle},
  journal={Traffic},
  year={2005},
  volume={6 4},
  pages={
          286-302
        }
}
Dendritic cells (DCs) present antigens to T cells via CD1, HLA class I or class II molecules. During maturation, HLA class II-restricted presentation is optimized. The relocalization of CD1e from Golgi to endosomal compartments during DC maturation suggests also an optimization of the antigen-presentation pathway via CD1 molecules. We here detail the biosynthesis and cellular pathway of CD1e in immature and maturing DCs. Unlike the other CD1 molecules, CD1e was found to reach late endosomes… CONTINUE READING
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