The cellular orchestra in skin allergy; are differences to lung and nose relevant?

  title={The cellular orchestra in skin allergy; are differences to lung and nose relevant?},
  author={M{\"u}beccel Akdis},
  journal={Current opinion in allergy and clinical immunology},
  volume={10 5},
PURPOSE OF REVIEW It has been a long lasting question that although a similar peripheral allergen-specific immune response has been observed, why some patients show only atopic dermatitis, rhinitis and asthma alone or their combinations. The answer resides in the propensity of resident tissue cells and local antigen-presenting cells and T cells for developing an allergic inflammatory immune response. Antigen-presenting cells introduce processed allergens to T helper lymphocytes, where a… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 13 extracted citations


Publications referenced by this paper.
Showing 1-10 of 97 references

CD 56 highCD 16CD 62 LNK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses

  • T Carbone, F Nasorri, D Pennino
  • J Immunol
  • 2010

Natural killer cells in atopic and autoimmune diseases of the skin

  • D vonBubnoff, E Andres, F Hentges
  • J Allergy Clin Immunol
  • 2010

Basophils function as antigen - presenting cells for an allergeninduced T helper type 2 response

  • CL Sokol, NQ Chu, S Yu
  • Nat Immunol
  • 2009

Similar Papers

Loading similar papers…