The cellular neurobiology of depression

  title={The cellular neurobiology of depression},
  author={Husseini K. Manji and Wayne C. Drevets and Dennis S. Charney},
  journal={Nature Medicine},
Major depressive disorders, long considered to be of neurochemical origin, have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways may hold promise as new therapeutics for depression. 
Highly Influential
This paper has highly influenced 22 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.
409 Citations
69 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 409 extracted citations


Publications referenced by this paper.
Showing 1-10 of 69 references

Antidepressant effects of ketamine in depressed patients

  • R. M. Berman
  • Biol . Psychiatry
  • 2000

Similar Papers

Loading similar papers…