The cellular mechanisms of the antiemetic action of dexamethasone and related glucocorticoids against vomiting.

@article{Chu2014TheCM,
  title={The cellular mechanisms of the antiemetic action of dexamethasone and related glucocorticoids against vomiting.},
  author={Chin-Chen Chu and Chung-Hsi Hsing and Ja-ping Shieh and Chih-Chiang Chien and Chiu-Ming Ho and Jhi-Joung Wang},
  journal={European journal of pharmacology},
  year={2014},
  volume={722},
  pages={48-54}
}
Glucocorticoids, used primarily as anti-allergic and anti-inflammatory drugs, are also effective, alone or combined with other antiemetics, for preventing nausea and vomiting. Dexamethasone, one of the glucocorticoids, has been suggested as a first-line drug for preventing low-level emetogenic chemotherapy- and radiotherapy-induced nausea and vomiting, and in patients with only one or two risks for postoperative nausea and vomiting (PONV). Dexamethasone combined with 5-HT3 or tachykinin NK1… CONTINUE READING