The cellular electrophysiologic effect of a new amiodarone like antiarrhythmic drug GYKI 16638 in undiseased human ventricular muscle: comparison with sotalol and mexiletine.

@article{Opincariu2002TheCE,
  title={The cellular electrophysiologic effect of a new amiodarone like antiarrhythmic drug GYKI 16638 in undiseased human ventricular muscle: comparison with sotalol and mexiletine.},
  author={Mikl{\'o}s Opincariu and Andr{\'a}s Varr{\'o} and Norbert Iost and L{\'a}szl{\'o} Vir{\'a}g and Ott{\'o} H{\'a}la and Jenno Szolnoki and J{\'a}nos Sz{\'e}csi and G{\'a}bor Bog{\'a}ts and P{\'a}l Szenohradszky and P{\'e}ter M{\'a}tyus and Julius Gy Papp},
  journal={Current medicinal chemistry},
  year={2002},
  volume={9 1},
  pages={
          41-6
        }
}
The cellular electrophysiologic effect of GYKI 16638, a new antiarrhythmic compound was studied and compared with that of sotalol and mexiletine in undiseased human right ventricular muscle preparation by applying the conventional microelectrode technique. GYKI 16638 (5 microM), at stimulation cycle length of 1000 ms, lengthened action potential duration… CONTINUE READING