The cellular chaperone heat shock protein 90 facilitates Flock House virus RNA replication in Drosophila cells.

Abstract

The assembly of viral RNA replication complexes on intracellular membranes represents a critical step in the life cycle of positive-strand RNA viruses. We investigated the role of the cellular chaperone heat shock protein 90 (Hsp90) in viral RNA replication complex assembly and function using Flock House virus (FHV), an alphanodavirus whose RNA-dependent… (More)

Topics

6 Figures and Tables