The cellular and physiological mechanism of wing-body scaling in Manduca sexta.

@article{Nijhout2010TheCA,
  title={The cellular and physiological mechanism of wing-body scaling in Manduca sexta.},
  author={H. Nijhout and Laura W. Grunert},
  journal={Science},
  year={2010},
  volume={330 6011},
  pages={1693-5}
}
In animals, appendages develop in proportion to overall body size; when individual size varies, appendages covary proportionally. In insects with complete metamorphosis, adult appendages develop from precursor tissues called imaginal disks that grow after somatic growth has ceased. It is unclear, however, how the growth of these appendages is matched to the already established body size. We studied the pattern of cell division in the tobacco hornworm Manduca sexta and found that both the rate… CONTINUE READING

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