The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma.

Abstract

Oral squamous cell carcinomas (SCCs) are malignant tumours that frequently invade the mandibular bone and bone invasion is a common clinical problem. Recent studies have revealed that bone resorption by osteoclasts is an important step in the process of bone invasion by oral SCCs. However, the cellular and molecular mechanisms of bone invasion by oral SCCs… (More)
DOI: 10.1111/j.1601-0825.2010.01781.x

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