The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases

@inproceedings{Rueda2016TheCA,
  title={The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases},
  author={Elda M. Rueda and Jerry E. Johnson and Anand Giddabasappa and Anand Swaroop and Matthew John Brooks and Irena Sigel and Shawnta Y. Chaney and Donald A. Fox},
  booktitle={Molecular vision},
  year={2016}
}
PURPOSE The homeostatic regulation of cellular ATP is achieved by the coordinated activity of ATP utilization, synthesis, and buffering. Glucose is the major substrate for ATP synthesis through glycolysis and oxidative phosphorylation (OXPHOS), whereas intermediary metabolism through the tricarboxylic acid (TCA) cycle utilizes non-glucose-derived monocarboxylates, amino acids, and alpha ketoacids to support mitochondrial ATP and GTP synthesis. Cellular ATP is buffered by specialized equilibrium… CONTINUE READING