The cells and peripheral representation of sodium taste in mice

@inproceedings{Chandrashekar2010TheCA,
  title={The cells and peripheral representation of sodium taste in mice},
  author={Jayaram Chandrashekar and Christina Kuhn and Yuki Oka and David A. Yarmolinsky and Edith Hummler and Nicholas J P Ryba and Charles S. Zuker},
  booktitle={Nature},
  year={2010}
}
Salt taste in mammals can trigger two divergent behavioural responses. In general, concentrated saline solutions elicit robust behavioural aversion, whereas low concentrations of NaCl are typically attractive, particularly after sodium depletion. Notably, the attractive salt pathway is selectively responsive to sodium and inhibited by amiloride, whereas the aversive one functions as a non-selective detector for a wide range of salts. Because amiloride is a potent inhibitor of the epithelial… CONTINUE READING
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