The cell wall of Paracoccidioides brasiliensis: insights from its transcriptome.

@article{Tomazett2005TheCW,
  title={The cell wall of Paracoccidioides brasiliensis: insights from its transcriptome.},
  author={Patr{\'i}cia Kott Tomazett and Aline Helena da Silva Cruz and Sheyla Maria Rondon Caixeta Bonfim and C{\'e}lia Maria de Almeida Soares and Maristela Pereira},
  journal={Genetics and molecular research : GMR},
  year={2005},
  volume={4 2},
  pages={309-25}
}
The cell wall of a human pathogenic fungus is in contact with the host, serves as a barrier against host defense mechanisms and harbors most fungal antigens. In addition, cell wall biosynthesis pathways have been recognized as essential to viability and as specific drug targets. Paracoccidioides brasiliensis is a dimorphic fungus that presents mycelium morphology in the free environment and causes infection in a yeast form. The morphogenetic conversion is correlated with changes in the cell… CONTINUE READING
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