The cell surface expression of group 2 capsular polysaccharides in Escherichia coli: the role of KpsD, RhsA and a multi-protein complex at the pole of the cell.

@article{McNulty2006TheCS,
  title={The cell surface expression of group 2 capsular polysaccharides in Escherichia coli: the role of KpsD, RhsA and a multi-protein complex at the pole of the cell.},
  author={Clodagh McNulty and James Thompson and Brendan Barrett and Liz Lord and Christian Andersen and Ian S Roberts},
  journal={Molecular microbiology},
  year={2006},
  volume={59 3},
  pages={907-22}
}
The export of large negatively charged capsular polysaccharides across the outer membrane represents a significant challenge to Gram negative bacteria. In the case of Escherichia coli group 2 capsular polysaccharides, the mechanism of export across the outer membrane was unknown, with no identified candidate outer membrane proteins. In this paper we demonstrate that the KpsD protein, previously believed to be a periplasmic protein, is an outer membrane protein involved in the export of group 2… CONTINUE READING