The cell cycle-related genes as biomarkers for schizophrenia

  title={The cell cycle-related genes as biomarkers for schizophrenia},
  author={Satoshi Okazaki and Shuken Boku and Ikuo Otsuka and Kentaro Mouri and Akitoyo Hishimoto},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
BACKGROUND Recent studies suggest that genomic abnormalities such as single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) may elevate the risk of schizophrenia. Such genomic abnormalities often occur during chromosomal DNA replication in the S phase of cell cycle. In addition, several studies showed that abnormal expressions of several cell cycle-related genes are associated with schizophrenia. Therefore, here we compared mRNA expression levels of cell cycle-related genes in… CONTINUE READING


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