The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development.

@article{Copani2008TheCC,
  title={The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development.},
  author={Agata G. Copani and Salvatore Guccione and Laura Giurato and Filippo Caraci and Marco Calafiore and Maria Angela Sortino and Ferdinando Nicoletti},
  journal={Current medicinal chemistry},
  year={2008},
  volume={15 24},
  pages={
          2420-32
        }
}
Alzheimer's disease (AD), the leading cause of senile dementia, has become a considerable social and economical problem. Current AD therapeutics provide mainly symptomatic short-term benefit, rather than targeting disease mechanisms. The hallmarks for AD are beta-amyloid plaques, neurofibrillary tangles, and regionalized neuronal loss. Additional… CONTINUE READING