The cell cycle dependence of protein synthesis during Xenopus laevis development.

@article{Kanki1991TheCC,
  title={The cell cycle dependence of protein synthesis during Xenopus laevis development.},
  author={John P. Kanki and John W. Newport},
  journal={Developmental biology},
  year={1991},
  volume={146 1},
  pages={198-213}
}
The regulation of early embryonic development in the amphibian Xenopus laevis depends largely upon translational and post-translational regulatory mechanisms to direct the complex cytodifferentiations that take place during early cleavage and blastula formation. The cell cycle dependence of protein synthesis was examined in developing Xenopus embryos as well as in cycling cell-free lysates from Xenopus eggs. In both cases M-phase and the activation of the M-phase kinase were found to be… CONTINUE READING