The cell and molecular biology of glaucoma: axonopathy and the brain.

  title={The cell and molecular biology of glaucoma: axonopathy and the brain.},
  author={David J. Calkins and Philip J. Horner},
  journal={Investigative ophthalmology & visual science},
  volume={53 5},
Many ophthalmologists and members of the lay public alike view glaucoma in its historical context—that is, as exclusively a disease of the eye. This view has been (and remains) overwhelmingly pervasive because the etiology of the disease involves so many factors associated with the eye: intraocular pressure (IOP), corneal thickness, optic disc morphology, and so on. Glaucoma is associated with sensitivity to IOP, and lowering IOP through either topical application of hypotensive drugs or… CONTINUE READING


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Proceedings of the National Academy of Sciences of the United States of America • 2010
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Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2008
View 2 Excerpts

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